| ncRNA name | hsa-miR-31 |
| ncRNA Category | miRNA |
| Disease name | retinoblastoma (RB) |
| Species | Homo sapiens |
| Tissues/Cell_line | normal pediatric retina and RB samples; human RB cell lines Y79 and WERI-RB1 |
| Methods | qRT-PCR, transfection, luciferase reporter assay, microarray, immunofluorescence staining, Western blot, immunohistochemistry |
| Expression pattern | down-regulated |
| Functional description | miRNAs-31 and -200a expression is significantly reduced in human retinoblastomas. Moreover, overexpression of these two miRNAs restricts the expansion of a highly proliferative cell line (Y79), but does not restrict the growth rate of a less aggressive cell line (Weri1). |
| PubMed ID | 26379276 |
| Year | 2015 |
| Title | Novel miRNA-31 and miRNA-200a-Mediated Regulation of Retinoblastoma Proliferation. |
| Drug-related ncRNA | NO |
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